Endocrine Abstracts

Background: The diagnosis of pheochromocytoma and paraganglioma (PPGL) requires the measurement of plasma metanephrines; however, several pre-analytical parameters can lead to false positive test results. During venipuncture, pain perception may activate the sympathetic nervous system, increasing catecholamine metabolite levels. Furthermore, hypertension patients exhibit sympathetic hyperactivity compared to normotensive subjects. The purpose of this study was to compare the p...

Introduction: Multiple endocrine neoplasia type 2A (MEN 2A) is an autosomal dominant disorder from a RET proto-oncogene mutation, characterized by the presence of medullary thyroid carcinoma (MTC), pheochromocytoma and/or primary hyperparathyroidism.Materials and Methods: A retrospective study of 5 probands (3 males and 2 females, age range 31–46 years) and 6 family members (2 males and 4 females, age range 2–50 years) diagnosed as MEN 2A at Ki...

Objective: Obesity is a risk factor for hypogonadotrophic hypogonadism in men. Increase in body weight was found to be associated with decrease testosterone level and sex hormone-binding globulin (SHBG) level. The aim of this study was to evaluate the change in testosterone levels in extremely obese men after bariatric surgery.Methods: This is a prospective study including 29 morbidly obese men undergoing bariatric surgery. Main outcomes were changes in ...

Background: Myxedema coma is an uncommon but life-threatening condition of severe and decompensated hypothyroidism requiring early recognition and prompt treatment. The aim of this study is to describe the clinical features and identify factors associated with mortality of our patients diagnosed myxedema coma over the past 15 years.Materials and methods: Retrospective chart review of patients diagnosed and treated at King Chulalongkorn Memorial Hospital ...